QVZ: lossy compression of quality values

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QVZ: lossy compression of quality values

MOTIVATION Recent advancements in sequencing technology have led to a drastic reduction in the cost of sequencing a genome. This has generated an unprecedented amount of genomic data that must be stored, processed and transmitted. To facilitate this effort, we propose a new lossy compressor for the quality values presented in genomic data files (e.g. FASTQ and SAM files), which comprise roughly...

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Recent advancements in sequencing technology have led to a drastic reduction in genome sequencing costs. This development has generated an unprecedented amount of data that must be stored, processed, and communicated. To facilitate this effort, compression of genomic files has been proposed. Specifically, lossy compression of quality scores is emerging as a natural candidate for reducing the gr...

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ژورنال

عنوان ژورنال: Bioinformatics

سال: 2017

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/btx654